What is the OREXIN B (HUMAN)?

OREXIN B (HUMAN) is White lyophilised solid, while it's Molecular Formula is C123H212 N44 O35 S. White lyophilised solid Used in Pharmaceutical Industry: Orexin B (Human) is used as a research tool for studying the role of orexin receptors in various physiological processes, such as feeding behavior, wakefulness, and motivation. Its agonistic properties make it valuable for investigating the mechanisms underlying these processes and for developing potential therapeutic agents targeting orexin receptors. Used in Neuroscience Research: Orexin B (Human) is used as a research compound in neuroscience to explore the neural circuits and signaling pathways involved in the regulation of feeding behavior, wakefulness, and motivation. This helps researchers better understand the complex interplay between the central nervous system and these physiological processes, potentially leading to the development of novel treatments for related disorders. Used in Drug Discovery and Development: Orexin B (Human) is used as a lead compound in drug discovery and development efforts aimed at targeting orexin receptors for the treatment of various disorders, such as sleep disorders, eating disorders, and addiction. Its ability to modulate orexin receptor activity makes it a promising starting point for designing new therapeutic agents with improved efficacy and safety profiles.

What is the CAS number for OREXIN B (HUMAN)?

The CAS number of OREXIN B (HUMAN) is 205640-91-1.

What is OREXIN B (HUMAN) (205640-91-1) used for?

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC50 values of 420 and 36 nM for human recombinant OX1 and OX2 receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.

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Orexin B

CasNo:205640-91-1
Purity:
Molecular Formula:C123H212 N44 O35 S
Molecular Weight:2899.34
Melting Point:
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