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What is the ANP 1-28, HUMAN ?

ANP 1-28, HUMAN is , while it's Molecular Formula is C127H203N45O39S3. Treatment of decompensated congestive heart failure.

What is the CAS number for ANP 1-28, HUMAN ?

The CAS number of ANP 1-28, HUMAN is 89213-87-6.

More information of ANP 1-28, HUMAN 89213-87-6 are:

Synonyms	Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-proline-5-de-L-arginine-17-L-methionine-;1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane,cyclic peptide deriv.;(1-28)-Human atrial natriuretic peptide;13: PN:US20060171920 SEQID: 13 claimed protein;2: PN: US6028055 SEQID: 51 claimedprotein;4: PN: US20090011997 SEQID: 2 claimed protein;56: PN: US20090011997SEQID: 59 claimed protein;82: PN: US20080153747 SEQID: 82 claimed protein;Atriopeptin (human a-component);Carperitide;Horse atrial natriuretic peptide-28;Humanatrial natriuretic factor (99-126);Human atrial natriuretic peptide (1-28);Human atrial natriuretic peptide (99-126);Human atriopeptin(1-28);Humanatriopeptin(99-126);Human atriopeptin-28;Human a-atrial natriuretic factor;Human a-atrial natriuretic factor(1-28);Human a-atrial natriuretic peptide;Human a-atriopeptin;L-Tyrosine,L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-a-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-,cyclic (7?;SUN 4936;[99-126]-Human proatriopeptin;a-Atriopeptin (human);a-Human atrial natriuretic hormone;a-Human atrial natriuretic peptide (1-28);a-Human atrial natriureticpolypeptide;a-Humanatriopeptin(1-28);
CAS Number	89213-87-6
Molecular Formula	C127H203N45O39S3
Molecular Weight	3080.48
Density	1.55 g/cm³
PSA	1479.28000
LogP	-2.10540

What is ANP 1-28, HUMAN (89213-87-6) used for?

Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, inhibit renin secretion, and increase sodium excretion. Human ANP binds to ANP receptors on cultured vascular smooth muscle cells (VSMCs) with a Kd value of approximately 1-2 nM and increases cGMP levels in a dose-dependent manner. It relaxes potassium-induced contraction of isolated canine renal arterial strips when used at concentrations of 10 and 100 ng/ml and dilates renal arteries in anesthetized dogs when used at doses ranging from 10 to 100 ng/kg. In a rat model of heart failure following experimental autoimmune myocarditis, human ANP, via osmotic mini pump for 28 days, decreases cardiomyocyte size as well as the amount of cardiac fibrosis and left ventricular remodeling. ANP (1-28) (human) is a 28 amino acid peptide corresponding to the human protein sequence.

InChI:InChI=1/C127H203N45O39S3/c1-9-64(6)99-121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)60-213-214-61-90(171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173)120(208)162-80(45-66-21-12-10-13-22-66)103(191)147-50-93(181)146-51-95(183)152-71(25-16-37-141-123(131)132)105(193)160-77(36-42-212-8)110(198)165-83(49-98(186)187)115(203)159-75(111(199)172-99)29-20-41-145-127(139)140/h10-15,21-24,30-33,62-65,70-90,99,173-178H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,

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