What is the Pramiracetam?

Pramiracetam is white crystalline powder, while it's Molecular Formula is C14H27N3O2. white crystalline powder Pramiracetam is an inhibitor of PREP and anti-migraine agent. It is a more potent nootropic drug derived from piracetam. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. It was also effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins.

What is the CAS number for Pramiracetam?

The CAS number of Pramiracetam is 68497-62-1.

What is Pramiracetam (68497-62-1) used for?

Pramiracetam as a pyrrolidones cerebral metabolism improving drug,is a kind of CNS drugs that can help improve memory, anti-forgetful , it is developed by the United States Parke-Davis pharmaceutical companies, with a strong improvement in brain function, enhancing memory, the ability to promote brain alertness, and clinical trials have proved that its activity is 6-13 times of piracetam, 3-4 times of oxiracetam, 1.25 times of aniracetam, and it is toxicity low and well tolerated, it can be used for long-term medication to improve symptoms, and delay Alzheimer-type dementia.Clinically relevant for elderly people attention and memory disorders, benign forgetfulness of aging, senile dementia (Alzheimer's disease) prevention, enhancing memory. Pramiracetam also applies to dilate blood vessels bodybuilding health products additives.InChI:InChI=1/C14H27N3O2/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19/h11-12H,5-10H2,1-4H3,(H,15,18)

Factory supply Pramiracetam 68497-62-1 with sufficient stock and high standard

Molecular Formula:C14H27N3O2
Molecular Weight:269.387
Appearance/Colour:white crystalline powder
Vapor Pressure:1.11E-08mmHg at 25°C
Melting Point:47-48°
Refractive Index:1.495
Boiling Point:461 °C at 760 mmHg
PKA:14.76±0.46(Predicted)
Flash Point:232.6 °C
PSA：52.65000
Density:1.036 g/cm³
LogP:1.17260

Pramiracetam(Cas 68497-62-1) Usage


Definition	ChEBI: Pramiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.
Brand name	Remen (ParkeDavis).

InChI:InChI=1/C14H27N3O2/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19/h11-12H,5-10H2,1-4H3,(H,15,18)

68497-62-1 Relevant articles

Pramiracetam hydrate crystal and preparation method thereof

-

Paragraph 0122; 0126-0127; 0133; 0137-0138; 0144; 0148; ..., (2021/07/31)

The invention relates to the technical f...

The preparation method of N, N - diisopropylethylenediamine. Preparation method of

-

Paragraph 0055; 0129; 0158-0166, (2021/08/25)

N, N -isopropyl N chloroethylamine hydro...

Industrial preparation method of pramiracetam sulfate

-

, (2020/04/02)

The invention relates to the field of pr...

Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams

Cioc, R?zvan C.,Schaepkens van Riempst, Lola,Schuckman, Peter,Ruijter, Eelco,Orru, Romano V. A.

, p. 1664 - 1674 (2017/03/21)

We report the synthesis of racetams, a d...

68497-62-1 Process route

: 616-45-5
2-pyrrolidinon

: N-[2-(di(isopropyl)amino)ethyl]-2-chloroacetamide

: 68497-62-1
pramiracetam

Conditions

Conditions	Yield
2-pyrrolidinon; With sodium methylate; In toluene; at 105 - 108 ℃; for 3h; N-[2-(di(isopropyl)amino)ethyl]-2-chloroacetamide; In toluene; at 60 - 70 ℃;	89.49%
2-pyrrolidinon; With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h; N-[2-(di(isopropyl)amino)ethyl]-2-chloroacetamide; In tetrahydrofuran; for 10h; Solvent; Reagent/catalyst; Reflux;

: 616-45-5
2-pyrrolidinon

: N-(2-diisopropylaminoethyl)chloroacetamide hydrochloride

: 68497-62-1
pramiracetam

Conditions

Conditions	Yield
2-pyrrolidinon; With sodium ethanolate; In toluene; at 80 - 105 ℃; Inert atmosphere; N-(2-diisopropylaminoethyl)chloroacetamide hydrochloride; In toluene; at 40 - 80 ℃;	83.2%

68497-62-1 Upstream products

61516-73-2
2-(oxo-pyrrolidin-1-yl)-acetic acid ethyl ester
121-05-1
N',N'-diisopropyl-ethane-1,2-diamine
616-45-5
2-pyrrolidinon

68497-62-1 Downstream products

72869-16-0
Pramiracetam sulfate

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Pramiracetam